Disease is characterized by a cholinergic-type neurochemical deficit , its pharmacological treatment was initially developed as a substitution therapy. This reasoning was followed taking into account that dopaminergic replacement had shown efficacy in parkinson's disease. Subsequently, and as a result of other research, another therapeutic strategy was developed based on the modulation of glutamatergic hyperexcitability from the modulation of the n-methyl-d-aspartate (nmda) receptor, the main molecular device for the control of synaptic
plasticity and memory function. The main drugs used are listed below according to the purpose of the treatment. Medications to slow the progression of symptoms of alzheimer's disease there is a type of pharmacological treatment that delays the evolution of the symptoms of alzheimer's disease. However, they do not act on brain injuries nor do they extend the life expectancy of patients. Within this group are the acetylcholinesterase enzyme e commerce photo editing service inhibitors (donepezil, rivastigmine and galantamine) and memantine, which is a modulator of the effect of the pathological elevation of tonic glutamate levels. Inesem business school master in pharmacology and pharmaceutical technology more information medications to combat behavior and mood disorders alzheimer's disease is
characterized by behavior and mood disorders from its onset. There are some medications that have been shown to decrease the frequency and severity of behavioral disorders to some extent . These are anxiolytics, antidepressants, cholinesterase inhibitors with positive action on apathy, hypnotics and antipsychotics . However, all of the drugs listed above have restricted use and many long-term side effects. What is the current status of clinical trials on alzheimer's disease? To develop new drugs, a series of phases that constitute a clinical trial must be followed and passed . In this sense, a drug must be subjected to
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